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08 Pain and palliative care MCQs

Davidson's Medicine - Part 1: Fundamentals of Medicine · Davidson's Principles of Medicine · 11 practice questions

1. A patient with malignant bowel obstruction not for surgery has colic and large-volume vomiting; another has constant nausea with hypercalcaemia. Which management fits?

  1. AOctreotide and hyoscine butylbromide for the first, treating the reversible cause for the second
  2. BMetoclopramide for the first, steroids for the second
  3. CCyclizine alone for both
  4. DNasogastric tube alone for both
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A. Octreotide and hyoscine butylbromide for the first, treating the reversible cause for the second Octreotide reduces secretions and hyoscine treats colic; hypercalcaemia and constipation are reversible causes; metoclopramide is generally avoided with colic.

2. A patient with cancer cachexia has lost 10 kg with anorexia and muscle wasting. Which measures are recommended?

  1. ABed rest
  2. BLong-term steroids
  3. CFish oil as proven treatment
  4. DExercise to maintain muscle, adequate calories and supplements, with short-term steroids only for appetite
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D. Exercise to maintain muscle, adequate calories and supplements, with short-term steroids only for appetite Steroids boost appetite temporarily but cause fluid retention, so generally short-term only; exercise maintains muscle mass.

3. A patient on an SSRI for chronic pain wants an herbal remedy and another drinks grapefruit juice. Which interactions are described?

  1. AGinkgo increases serotonin
  2. BGrapefruit lowers levels of all drugs
  3. CHerbal remedies never interact
  4. DSt John's wort increases serotonergic effects with antidepressants and grapefruit may too
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D. St John's wort increases serotonergic effects with antidepressants and grapefruit may too St John's wort and grapefruit may increase serotonergic effects with some antidepressants; ginkgo may increase bleeding time with paracetamol.

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