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USMLE Step 1: format, content outline and fees

Step 1 tests whether you can apply the basic sciences to the practice of medicine. It is a one-day computer exam, scored pass/fail, and it is the first Step most international medical graduates take.

Checked against the official sources below on 21 October 2026.

At a glance

FormatFourteen 30-minute blocks in one 8-hour day (for tests on or after 14 May 2026)[1]
QuestionsAbout 280 multiple-choice questions, no more than 20 in a block[1][2]
BreaksAt least 55 minutes of break time, plus an optional 5-minute tutorial; finishing a block early adds to your break[1]
ScoringPass/fail only, for exams taken on or after 26 January 2022[3]
Passing standard196 on the three-digit scale (only pass or fail is reported)[3]
ResultsUsually within four weeks of your test date[3]
AttemptsFour per Step, incomplete attempts included; no more than three tries at the same Step in 12 months[4]
Who can sit it as an IMGStudents and graduates of a medical school outside the US that the World Directory of Medical Schools lists as meeting ECFMG's requirements[4]
Where IMGs applyThrough FSMB (since 12 January 2026), no longer through ECFMG[5][6]
Fee for IMGsUS$695, plus a US$210 region fee to test outside the US and Canada[5]
Test centresPrometric test centres; you choose one on the Prometric website when you schedule[7]

Syllabus

USMLE publishes how much of the exam each area makes up. A question can count towards more than one discipline, so the discipline ranges add up to more than 100%.

By system (% of the exam)[8]

  1. Human development 1-3%
  2. Blood and lymphoreticular/immune systems 9-13%
  3. Behavioral health and nervous systems/special senses 10-14%
  4. Musculoskeletal, skin and subcutaneous tissue 8-12%
  5. Cardiovascular system 7-11%
  6. Respiratory and renal/urinary systems 11-15%
  7. Gastrointestinal system 6-10%
  8. Reproductive and endocrine systems 12-16%
  9. Multisystem processes and disorders 8-12%
  10. Biostatistics and epidemiology/population health 4-6%
  11. Social sciences: communication and interpersonal skills 6-9%

By discipline (% of the exam)[8]

  1. Pathology 45-55%
  2. Physiology 30-40%
  3. Nutrition 15-20%
  4. Gross anatomy and embryology 10-20%
  5. Microbiology 10-20%
  6. Pharmacology 10-20%
  7. Behavioral sciences 10-15%
  8. Biochemistry 5-15%
  9. Histology and cell biology 5-15%
  10. Immunology 5-15%
  11. Genetics 5-10%

By physician task (% of the exam)[8]

  1. Medical knowledge: applying foundational science concepts 60-70%
  2. Patient care: diagnosis 20-25%
  3. Communication and interpersonal skills 6-9%
  4. Practice-based learning and improvement 4-6%

Good to know

Build your basic sciences

Chapter-wise MCQs from medical textbooks, marked instantly with an explanation.

Practise MBBS questions

Sources

  1. USMLE: Step 1
  2. USMLE: 2027 Bulletin of Information (PDF)
  3. USMLE: Examination results and scoring
  4. USMLE Bulletin: Eligibility
  5. USMLE: Apply for exams
  6. USMLE: 2026 Bulletin information addendum
  7. USMLE Bulletin: Applying and scheduling
  8. USMLE: Step 1 content outline and specifications

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